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doi: 10.1016/j.celrep.2015.04.046 234 FisherFMKleinerSDourisNFoxECMepaniRJVerdeguerFet al
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JCI Insight 7 , e163795 (2022)
Pharmaceutical peptides are a schedule C controlled substance and they are being used at alarming rates in bodybuilding as of late
Cycle Guidelines Common Cagrilintide + Retatrutide Cycle Approaches Approach Full staggered titration Duration 24-week ramp + open-ended maintenance Off Period Community: 16-24 weeks on, 4-8 weeks off Best For Primary weight-loss strategy with full pathway coverage Approach Reta-first, cag add-on Duration Stabilize reta at 8-12 mg, then add cag for 12+ weeks Off Period Cag can be cycled on its own Best For Users already on retatrutide who want more satiety Approach Short-cycle test Duration 8-12 weeks at sub-maximal doses Off Period 4 weeks off Best For Initial tolerability check Taper retatrutide at the end of a cycle rather than stopping suddenly
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